Q: How is Folium’s water soluble technology superior to other water-soluble technology, liposomal or micelle-based, in the market?
A: Folium’s nanoemulsions are a finely-optimized formula that uses optimized composition and a unique process to manufacture. The average size of the hemp oil droplet is 25 nanometers, compared with 100-5000 nanometers that is usually obtained by using the industry standard liposomal delivery method. The small size of the Folium nanoemulsion leads to a much larger surface area of the hemp oil droplets in softgels, leading to much higher absorption in blood. Hemp oil nanoemulsions can also be used in a number of commercial areas, including the cosmetic, pharmaceutical and food industries. Their lipophilic (oily) interior (i.e. ability to dissolve in fats, oils, lipids, and non-polar solvents) makes them a much better option for transporting lipophilic compounds compared to liposomes, and as such they more efficiently enable the skin penetration of active ingredients. Furthermore, due to their transparent properties and extremely small droplet size, nanoemulsions do not lead to phase-separation (oil separating from water), and thus enable the formulation of sprayable products.
Q: How is Full-Spectrum Phytocannabinoid Hemp Oil better than using purified Cannabidiol isolate?
Q: How is Folium’s Full-Spectrum Phytocannabinoid Hemp Oil extracted? How is THC-removed from this oil?
A: The hemp plant material is dried and milled into a powdered form. This allows for higher surface area which in turn results in an efficient extraction in shorter time. The extraction is carried out either in supercritical CO2 or ethanol. The solvent allows for preferential extraction of canabinoids, waxes, terpernes and some of the impurities while discouraging the exchange of impurities such as plant carbohydrates and other impurities. The liquid extract or slurry containing plant material is processed through a custom designed filtration process in which almost all of the undissolved solids are retained while solid-free clean extract is able to permeate through the filter membrane. The solvent from clean hemp extract is recovered using distillation. This converts liquid extract into an oil form. This oil is further treated to preferentially remove waxes. It is then processed through a unique chromatography media which removes THC. The final oil has total phytocannabinoids in 75-85% range with total terpenes between 1 to 4%.
Q: Does Folium Biosciences practice organic farming? Does it have an organic certification?
A: Folium Biosciences believes in a cultivation approach that is compliant with organic farming practices as defined by the standards captured in the Organic Food Production Act, USDA organic regulations, and the National Organic Program. The farms at Folium practice an organic cultivation or handling system plan that intends to meet the requirements below:
- A description exists of practices and procedures to be performed and maintained;
- A list exists of each substance to be used as a production or handling input, indicating its
composition, source, and where it will be used;
- A description exists of the monitoring practices and procedures to be performed and maintained,
including the frequency with which they will be performed, to verify that the plan is effectively
- A description exists of the record-keeping system implemented to comply with the requirements;
- A description exists of the management practices and physical barriers established to prevent
commingling of organic and non-organic products on a split operation and to prevent contact of organic
production and handling operations and products with prohibited substances.
Folium Biosciences does not possess a certification to demonstrate that these organic farming practices have been reviewed and approved by a certification agency but expects to have one by 2018. This declaration intends to inform the parties concerned that the practices leading to an organic-certification in future are already in place and therefore, result in an equivalent product that could be expected from a certified-organic farm.