Answers to our most frequently asked questions. If you can’t find what you are looking for here, please don’t hesitate to contact us with questions. 

How is Folium Biosciences Full-Spectrum Phytocannabinoid-Rich (PCR) Hemp Oil extracted?
The hemp plant material is dried and milled into a powdered form. This allows for higher surface area and more efficient extraction over a short span of time. The extraction is carried out either in supercritical CO2 or ethanol allowing for preferential extraction of cannabinoids, waxes, and terpenes while discouraging the exchange of impurities such as plant carbohydrates and chlorophyll. The liquid extract or slurry containing plant material is processed through a custom designed filtration process in which almost all undissolved solids are retained while solid-free clean extract is able to permeate through the filter membrane. The solvent from clean hemp extract is recovered using distillation which converts liquid extract into an oil form after which the oil is treated to remove waxes, THC, and any remaining solvents.
How is THC removed from the PCR oil?
After the oil is extracted (see #9 above), it’s run through a unique chromatography media that removes THC. The final oil has phytocannabinoids in the 75-85% range with total terpenes between 1 to 4%.
Is CBD approved by the FDA
CBD Isolate has been used for various Investigational New Drug (IND) applications. GW Pharmaceuticals has an approval pending with the Food and Drug Administration for a drug with CBD as the active ingredient.
Is CBD oil legal to use?
Consumer products with full-spectrum hemp oil comprised of up to 80% CBD and no THC are legal and provide a solution for consumers who want a supply of CBD in a botanical extract.
Is Folium Biosciences product tested?
Yes, all of our products are tested for potency and purity in-house using HPLC test methods, with certificates of analysis and potency reports available for review. Folium Biosciences also works with independent labs, including Botanacor and iLab, to validate and verify our internal results. Each test ensures our product is solvent free and meets the strictest quality standards.
What are Folium Biosciences prices?
Folium Biosciences full product list can be found here. For bulk and wholesale pricing, please contact us.
What is a phytocannabinoid?
A phytocannabinoid is a naturally occurring compound produced by the cannabis plant. There are 113 known phytocannabinoids in cannabis including CBD and CBG. In addition to phytocannabinoids there are also synthetic cannabinoids used as drugs and endocannabinoids. Synthetic cannabinoids are artificially manufactured, whereas, endocannabinoids are naturally produced by humans and animals.
What are some applications for hemp oil?
A: Some applications for hemp oil include water-soluble powder, soft gel and capsules, topical formulations, sprays, tinctures, and functional beverages.
How is Folium Biosciences water-soluble technology superior to other liposomal or micelle-based technology in the market?
Folium Biosciences’s nanoemulsions are finely-engineered formulas using optimized composition and a unique manufacturing process. The more common microemulsion uses droplets roughly 1000nm in size. The lower surface area of microemulsions leads to less-effective and inconsistent absorption. With a nanoemulsion, the droplet size is 10-100 nanometers. The small size of Folium’s nanoemulsion leads to a much larger surface area of the hemp oil droplets, producing much higher absorption.
How much CBD oil should I use?
A: We always recommend that consumers work with their medical professionals to ensure they take the correct dosage. Consumers also have the right to request product testing from their chosen distributor before taking CBD oils regularly.
Full-Spectrum Phytocannabinoid Hemp Oil better than purified Cannabidiol isolate?
Full-spectrum phytocannabinoid-rich cannabidiol hemp oil is much more effective than a pure cannabidiol isolate due to synergistic properties of the other phytocannabinoid compounds and terpenes contained in full-spectrum hemp oil. PCR hemp oil is truly a case of the whole being greater than the sum of its parts. For a more detailed explanation see our blog post on this topic.
Why does CBD help with some medical conditions?
Our bodies possess an endogenous system called the endocannabinoid system. This system contains cannabinoid receptors that respond to phytocannabinoids. Theses cannabinoid receptors physically interact with phytocannabinoids initiating cell changes and producing effects that can holistically provide relief for a wide scope of ailments and symptoms.
Can you treat conditions with CBD oil?
Although you should always consult a doctor before using any treatment, people around the world are using holistic CBD oil to successfully treat a variety of conditions.
Do Folium’s products have any psychoactive components?
No. All Folium Biosciences products contain zero THC and therefore have no psychoactive effect. Our products are made with the highest grade 100% USA-grown hemp oil and are naturally rich in cannabinoids and terpenes.
Is Folium Biosciences licensed to produce hemp oil products?

Yes, all Folium Biosciences hemp is produced in accordance with Section 7606 of the 2014 US Farm Bill and registered with the Colorado State Department of Agriculture.


World Wide Services

Folium Biosciences is the largest, fully and vertically integrated producer of phytocannabinoid-rich (PCR) hemp oil in the world. We are a premier bulk supplier of highly refined 0.0% THC PCR hemp oil that can then be used for a multitude of consumer product applications.

Folium Biosciences is a B2B Wholesale Supplier and does not sell retail products.

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